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UNC-2170 maleate
CAS No. 2173992-60-2
UNC-2170 maleate( UNC2170 maleate )
Catalog No. M13477 CAS No. 2173992-60-2
A small molecule ligand for the methyl-lysine binding protein 53BP1 (p53-binding protein 1) with Kd of 22 uM against the 53BP1 tandem tudor domain.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameUNC-2170 maleate
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NoteResearch use only, not for human use.
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Brief DescriptionA small molecule ligand for the methyl-lysine binding protein 53BP1 (p53-binding protein 1) with Kd of 22 uM against the 53BP1 tandem tudor domain.
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DescriptionA small molecule ligand for the methyl-lysine binding protein 53BP1 (p53-binding protein 1) with Kd of 22 uM against the 53BP1 tandem tudor domain; highly cell permeant with no significant measureable cellular efflux; shows modestly potent, demonstrates at least 17-fold selectivity for 53BP1 as compared to nine other Kme reader proteins.
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In Vitro——
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In Vivo——
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SynonymsUNC2170 maleate
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PathwayApoptosis
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TargetMDM2-p53
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RecptorMDM2-p53
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Research Area——
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Indication——
Chemical Information
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CAS Number2173992-60-2
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Formula Weight429.3
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Molecular FormulaC18H25BrN2O5
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name3-bromo-N-(3-(tert-butylamino)propyl)benzamide maleate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Perfetti MT, et al. ACS Chem Biol. 2015 Apr 17;10(4):1072-81.
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